BDBM50507676 CHEMBL4592487

SMILES CC(C)(O)Cn1cc(cn1)-c1n[nH]c2ccnc(OC3CCOCC3)c12

InChI Key InChIKey=PCCQZRXZEOVGFU-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50507676   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50507676(CHEMBL4592487)Copy SMILESCopy InChI

Affinity DataIC50: 13nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin) by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50507676(CHEMBL4592487)Copy SMILESCopy InChI

Affinity DataKi:  21nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in insect cells using RtGWWRFYTLRRAR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL