BDBM50507840 CHEMBL4452291

SMILES C[C@H]([C@H](N)c1cn2cc(ccc2n1)C(C)(C)C)C(N)=O

InChI Key InChIKey=MHVVQGCDRSPVRZ-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507840   

TargetSodium channel protein type 10 subunit alpha(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50507840(CHEMBL4452291)Copy SMILESCopy InChI

Affinity DataIC50: 45nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
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TargetSodium channel protein type 5 subunit alpha(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50507840(CHEMBL4452291)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50507840(CHEMBL4452291)Copy SMILESCopy InChI

Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/19/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL