BDBM50508127 CHEMBL4449687

SMILES CCOc1ccc(cc1CC(O)=O)-c1ccc(CCCc2nn(-c3ccc(cc3)C(F)(F)F)c(=O)n2-c2ccccc2F)cc1

InChI Key InChIKey=YIUSVSPYCXFTHR-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50508127   

TargetPeroxisome proliferator-activated receptor delta(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 113nMAssay Description:Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Mouse)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 960nMAssay Description:Antagonist activity at mouse PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 1.28E+3nMAssay Description:Antagonist activity at mouse PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 1.04E+4nMAssay Description:Antagonist activity at ERbeta receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 1.83E+4nMAssay Description:Antagonist activity at mouse PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 2.13E+4nMAssay Description:Antagonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 2.23E+4nMAssay Description:Antagonist activity at glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 2.44E+4nMAssay Description:Antagonist activity at retinoid X receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at recombinant human PPARdelta after overnight incubation by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at recombinant human PPARalpha after overnight incubation by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.00E+4nMAssay Description:Agonist activity at PPARgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha/beta(Human)
Inception Sciences

Curated by ChEMBL
LigandPNGBDBM50508127(CHEMBL4449687)
Affinity DataIC50: 3.24E+4nMAssay Description:Antagonist activity at thyroid hormone receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed