BDBM50508260 CHEMBL4548634

SMILES Cn1nc(C2=C(C(=O)NC2=O)c2cn(CCCn3ccnc3)c3ccccc23)c2ccccc12

InChI Key InChIKey=RLPWMOBHRRCAES-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508260   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50508260(CHEMBL4548634)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-fused IDH1 R132H mutant expressed in Escherichia coli using alpha-ketoglutarate as substrate preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed