BDBM50508622 CHEMBL4526774

SMILES Cc1ccc(cc1)-c1cc([nH]n1)-c1cccc(NC(=O)c2ccc(c(c2)N2CCOCC2)C(F)(F)F)c1

InChI Key InChIKey=JEKPBRRCLQRVQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508622   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50508622(CHEMBL4526774)
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of CRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50508622(CHEMBL4526774)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed