BDBM50508623 CHEMBL4568629

SMILES CC(C)c1cc([nH]n1)-c1cccc(NC(=O)c2cc(cc(c2)C(F)(F)F)N2CCN(C)CC2)c1

InChI Key InChIKey=LBPACMVSPCBJSN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50508623   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50508623(CHEMBL4568629)
Affinity DataIC50: 110nMAssay Description:Inhibition of CRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50508623(CHEMBL4568629)
Affinity DataIC50: 700nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50508623(CHEMBL4568629)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of wild-type BRAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed