BDBM50509429 CHEBI:71578::CHEMBL1229884

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2CO[P@](O)(=O)O[C@@H]3[C@@H](CO[P@](O)(=O)O[C@H]2[C@H]1O)O[C@H]([C@@H]3O)n1cnc2c(N)ncnc12

InChI Key InChIKey=PDXMFTWFFKBFIN-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50509429   

TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509429(CHEBI:71578 | CHEMBL1229884)
Affinity DataEC50:  51nMAssay Description:Agonist activity at STING (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509429(CHEBI:71578 | CHEMBL1229884)
Affinity DataEC50:  200nMAssay Description:Activation of recombinant human STING haplotype G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by brigh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509429(CHEBI:71578 | CHEMBL1229884)
Affinity DataEC50:  200nMAssay Description:Activation of recombinant human STING haplotype R71H/G230A/R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509429(CHEBI:71578 | CHEMBL1229884)
Affinity DataEC50:  260nMAssay Description:Activation of wild-type human STING expressed in digitonin treated HEK293T cells co-expressing IRF3-activated ISRE assessed as IRF3 reporter activati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509429(CHEBI:71578 | CHEMBL1229884)
Affinity DataEC50:  300nMAssay Description:Activation of recombinant human wild-type STING expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-luciferase re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509429(CHEBI:71578 | CHEMBL1229884)
Affinity DataEC50:  7.10E+3nMAssay Description:Activation of recombinant human STING haplotype R293Q mutant expressed in 293T cells measured after 30 mins in presence of digitonin A by bright Glo-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509429(CHEBI:71578 | CHEMBL1229884)
Affinity DataEC50:  1.49E+4nMAssay Description:Activation of recombinant human wild-type STING expressed in 293T cells incubated for 7 hrs in absence of digitonin A by bright Glo-luciferase report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed