BDBM50509520 CHEMBL4539920

SMILES Cn1ccc(n1)-c1cncc(CNc2cc(ccc2F)C(=O)Nc2cccc(OC(F)(F)F)c2)c1

InChI Key InChIKey=IZKVIUJIUTXIRH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509520   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509520(CHEMBL4539920)
Affinity DataIC50: 0.708nMAssay Description:Inhibition of FLAG-tagged DDR1 in human HEK293 cells assessed as reduction in collagen-1-induced DDR1 phosphorylation incubated for 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509520(CHEMBL4539920)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50509520(CHEMBL4539920)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed