BDBM50509710 CHEMBL4447258

SMILES [O-][N+](=O)c1cccc(c1)-n1cc(COc2ccc(C=NNc3c4CCCCc4nc4ccccc34)cc2)nn1

InChI Key InChIKey=VNUMIBCAIFARQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509710   

TargetCholinesterase(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509710(CHEMBL4447258)
Affinity DataIC50: 48nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for 180 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509710(CHEMBL4447258)
Affinity DataIC50: 66nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 10 mins by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50509710(CHEMBL4447258)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate pre-incubated for 20 mins before substrate addition and measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed