BDBM50509781 CHEMBL4450852

SMILES OC(=O)CC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=MLLGKYJIOWULMN-QMOZSOIISA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50509781   

TargetCatenin beta-1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50509781(CHEMBL4450852)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50509781(CHEMBL4450852)
Affinity DataKd:  420nMAssay Description:Binding affinity to beta catenin (unknown origin) assessed as dissociation constant by VP-ITC methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCatenin beta-1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50509781(CHEMBL4450852)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed