BDBM50509863 CHEMBL4470701

SMILES CC(C)N(C)[C@@H]1CC[C@@H]([C@H](CS(C)(=O)=O)C1)N1CC[C@H](Nc2ncnc3ccc(cc23)C(F)(F)F)C1=O

InChI Key InChIKey=CJGHKRWUTQLMOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509863   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509863(CHEMBL4470701)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50509863(CHEMBL4470701)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in human HT1080 cells assessed as blockade of MIP1beta-binding to receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed