BDBM50510292 CHEMBL4471339

SMILES NC[C@H](Oc1noc2ncc(cc12)-c1ccccc1Cl)c1ccccc1

InChI Key InChIKey=VGOVVJRVKIMXAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510292   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50510292(CHEMBL4471339)
Affinity DataIC50: 500nMAssay Description:Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50510292(CHEMBL4471339)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK293 cells assessed as decrease in sodium current amplitude at -120 mV holding potential by Qpatch assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed