BDBM50510840 CHEMBL4456928

SMILES C(Nc1c2CCCCc2nc2ccccc12)c1ccc(cc1)-c1ccc(CNc2c3CCCCc3nc3ccccc23)cc1

InChI Key InChIKey=WIXYVLRIZYZCIN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50510840   

TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510840(CHEMBL4456928)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of human Acetylcholinesterase using acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510840(CHEMBL4456928)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition human BACE1 expressed in baculovirus expression system using Panvera peptide as substrate preincubated for 60 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50510840(CHEMBL4456928)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of human serum butyrylcholinesterase using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed