BDBM50510880 CHEMBL4436951

SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(Nc3ncnc4sc5COCCc5c34)cc2)ccc1Cl

InChI Key InChIKey=DVCZKXCJLLSBEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50510880   

TargetVascular endothelial growth factor receptor 2(Human)
University of Science & Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50510880(CHEMBL4436951)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal GST-tagged human VEGFR2 (805 to 1356 residues) expressed in a baculovirus infected Sf9 insect cell by Kinase-Glo Plus reagen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Srmpp

Curated by ChEMBL
LigandPNGBDBM50510880(CHEMBL4436951)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed