BDBM50511231 CHEMBL4514808
SMILES CN1CCc2c(C1)sc1nc([nH]c(=O)c21)-c1cc(C)c(OCCCCCC(=O)NO)c(C)c1
InChI Key InChIKey=BBFKONWWIAFKEJ-UHFFFAOYSA-N
Data 19 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50511231
TargetHistone deacetylase 1(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of HDAC1 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC2 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of HDAC6 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of HDAC3 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 167nMAssay Description:Inhibition of HDAC8 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Inhibition of GST-tagged BRD4 bromodomain (unknown origin) using biotinylated histone H4KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 923nMAssay Description:Inhibition of HDAC10 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant His-tagged BRD4 BD1 domain using H-SGRGK(Ac)GGK(Ac)GLGK-(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate preincubated with en...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of human recombinant His-tagged BRD4 BD2 domain using H-SGRGK(Ac)GGK(Ac)GLGK-(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate preincubated with en...More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 9(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human recombinant His-tagged BRD2 BD1 domain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by AlphaScreen assayMore data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant His-tagged BRDT BD1 domain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by AlphaScreen assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant His-tagged BRD3 BD2 domain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by AlphaScreen assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant His-tagged BRD2 BD2 domain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by AlphaScreen assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Sichuan University and Collaborative Innovation Center of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant His-tagged BRD3 BD1 domain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by AlphaScreen assayMore data for this Ligand-Target Pair