BDBM50511303 CHEMBL4434881

SMILES Cc1c(C)c(Oc2ccncc2)ccc1NC(=O)c1cccn(-c2ccc(F)cc2)c1=O

InChI Key InChIKey=JSQPARPVIOODMR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511303   

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50511303(CHEMBL4434881)
Affinity DataIC50: 180nMAssay Description:Displacement of fluorescein labeled ATP probe from full length His/GST-tagged RIPK3 (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50511303(CHEMBL4434881)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of fluorescein labeled ATP probe from His/GST-tagged c-Met (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50511303(CHEMBL4434881)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of fluorescein labeled ATP probe from full length His/GST-tagged RIPK1 (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50511303(CHEMBL4434881)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of fluorescein labeled ATP probe from His/GST-tagged RIPK2 (unknown origin) incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed