BDBM50511374 CHEMBL4522276
SMILES CC(C)CS(=O)(=O)NCc1cccc(c1)-c1ccc2c(NC(=O)C3CC3)n[nH]c2c1
InChI Key InChIKey=IIKPYJZUOZRTIB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 25 hits for monomerid = 50511374
TargetAP2-associated protein kinase 1(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged AAK1 kinase domain (31 to 396 residues) (unknown origin)...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase-like 2(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of FLAG-tagged full-length recombinant wild-type human CDKL2 expressed in HeLa cells using MBP as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
TargetBMP-2-inducible protein kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged BMP2K kinase domain (38 to 345 residues) (unknown origin...More data for this Ligand-Target Pair
TargetAP2-associated protein kinase 1(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of AAK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase-like 2(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of CDKL2 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetBMP-2-inducible protein kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of BMP2K (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 16(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataKi: 450nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged STK16 kinase domain (13 to 305 residues) (unknown origin...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase-like 2(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Displacement of tracer K10 from N-terminal NLuc-fused full-length CDKL2 (unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
TargetAP2-associated protein kinase 1(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused AAK1 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by N...More data for this Ligand-Target Pair
TargetAP2-associated protein kinase 1(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of tracer K10 from N-terminal NLuc-fused AAK1 (1 to 353 residues)(unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
TargetCyclin-G-associated kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged GAK kinase domain (12 to 347 residues) (unknown origin) ...More data for this Ligand-Target Pair
TargetBMP-2-inducible protein kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of tracer K10 from N-terminal NLuc-fused BMP2K (1 to 367 residues)(unknown origin) expressed in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
TargetBMP-2-inducible protein kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataIC50: 6.55E+3nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused BMP2K (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 16(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused STK16 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase-like 1(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLAG-tagged full-length recombinant wild-type human CDKL1 expressed in HeLa cells using MBP as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase-like 5(Homo sapiens)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLAG-tagged full-length recombinant wild-type human CDKL5 expressed in HeLa cells using MBP as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase-like 4(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLAG-tagged full-length recombinant wild-type human CDKL4 expressed in HeLa cells using MBP as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase-like 3(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLAG-tagged full-length recombinant wild-type human CDKL3 expressed in HeLa cells using MBP as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PRP4 homolog(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRP4 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetG protein-coupled receptor kinase 4(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GRK4 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PIP5K1A (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 5(Human)
University of North Carolina at Chapel Hill
Curated by ChEMBL
University of North Carolina at Chapel Hill
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK5 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SRPK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SRPK3 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
TargetCyclin-G-associated kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
University of North Carolina At Chapel Hill (Unc-Ch)
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused GAK (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by Na...More data for this Ligand-Target Pair