BDBM50511377 CHEMBL4534571

SMILES Fc1ccc(CS(=O)(=O)Nc2cccc(c2)-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)cc1

InChI Key InChIKey=KMVVQXBUHOYQKZ-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50511377   

TargetAP2-associated protein kinase 1(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511377(CHEMBL4534571)
Affinity DataKi:  59nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged AAK1 kinase domain (31 to 396 residues) (unknown origin)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBMP-2-inducible protein kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511377(CHEMBL4534571)
Affinity DataKi:  120nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged BMP2K kinase domain (38 to 345 residues) (unknown origin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 16(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511377(CHEMBL4534571)
Affinity DataKi:  430nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged STK16 kinase domain (13 to 305 residues) (unknown origin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511377(CHEMBL4534571)
Affinity DataKi:  7.00E+3nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged GAK kinase domain (12 to 347 residues) (unknown origin) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511377(CHEMBL4534571)
Affinity DataIC50:  9.24E+3nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused GAK (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBMP-2-inducible protein kinase(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511377(CHEMBL4534571)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused BMP2K (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 16(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511377(CHEMBL4534571)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused STK16 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Human)
University of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511377(CHEMBL4534571)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused AAK1 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed