BDBM50511606 CHEMBL4555389::US12110286, Example 10g

SMILES CCC(Cn1c2cc(Nc3ccnc(Cl)c3C#N)ccc2n(C)c1=O)C#N

InChI Key InChIKey=OBTOXJVNGXNYAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511606   

TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511606(CHEMBL4555389 | US12110286, Example 10g)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant His-tagged human BCL6 expressed in Escherichia coli BL21 AI cell incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511606(CHEMBL4555389 | US12110286, Example 10g)
Affinity DataIC50: 3.55E+3nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511606(CHEMBL4555389 | US12110286, Example 10g)
Affinity DataIC50: 4.17E+3nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent