BDBM50511627 CHEMBL4587209::US12110286, Example 36a

SMILES Cn1c2ccc(Nc3nc(ncc3Cl)N3CCC(F)(F)CC3)cc2n(CCC(C)(C)O)c1=O

InChI Key InChIKey=WBWCRVDICXCMSW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50511627   

TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511627(CHEMBL4587209 | US12110286, Example 36a)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant His-tagged human BCL6 expressed in Escherichia coli BL21 AI cell incubated for 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511627(CHEMBL4587209 | US12110286, Example 36a)
Affinity DataIC50: 331nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50511627(CHEMBL4587209 | US12110286, Example 36a)
Affinity DataIC50: 813nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent