BDBM50511676 CHEMBL4463076

SMILES CN(C)C(=O)c1ccc(cc1)-c1cnn2ccc(NCc3ccncc3)nc12

InChI Key InChIKey=CLEDTQHJEGRVQO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511676   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50511676(CHEMBL4463076)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of recombinant N-Terminal GST-tagged human RET V804M mutant (658 to end residues) incubated for 15 mins followed by substrate addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed