BDBM50511829 CHEMBL4515793

SMILES CCCN(CCC)NC(=O)C=Cc1ccc(CNCCc2c(C)[nH]c3ccccc23)cc1

InChI Key InChIKey=QNLMYRBFOJIBQX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50511829   

TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511829(CHEMBL4515793)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human C-terminal GST/His-tagged HDAC3 (1 to 428 residues) co-expressed with human N-terminal GST-tagged NCOR2 (395 to 489 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511829(CHEMBL4515793)
Affinity DataIC50: 413nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511829(CHEMBL4515793)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of recombinant human HDAC2 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50511829(CHEMBL4515793)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed