BDBM50511900 CHEMBL4454017::US11045448, Cpd. No. 72

SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](Cn1ccnn1)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)CC1)c1cccc(F)c1

InChI Key InChIKey=UDCCIJLZCSLTOS-ANCAAGCLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50511900   

TargetMenin(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50511900(CHEMBL4454017 | US11045448, Cpd. No. 72)
Affinity DataIC50:  2nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMenin(Homo sapiens (Human))
The Regents of The University of Michigan

US Patent
LigandPNGBDBM50511900(CHEMBL4454017 | US11045448, Cpd. No. 72)
Affinity DataIC50:  2nMAssay Description:Inhibition of fluorescent labeled tracer binding to Menin (unknown origin) after 1 hr by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed