BDBM50512214 CHEMBL4514473

SMILES OC(=O)c1cn(Cc2ccc(cc2)-n2cccn2)c2cc(NC[C@H]3CCNC3)c(F)cc2c1=O

InChI Key InChIKey=GSKYNQUKABOFSS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512214   

TargetDNA topoisomerase 1(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50512214(CHEMBL4514473)
Affinity DataIC50: 1.87E+5nMAssay Description:Inhibition of human topoisomerase 1 using supercoiled pBR322 plasmid DNA as substrate after 15 mins by ethidium bromide staining based agarose gel el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed