BDBM50512573 CHEMBL4476654

SMILES Cn1c(cc2c(Cl)c(Cl)ccc12)C(=O)NC1(COC1)c1ccc(cc1)C(CC(O)=O)c1cccnc1

InChI Key InChIKey=GAVIPRBFFNZNSO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512573   

TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Meyer Cancer Center

Curated by ChEMBL
LigandPNGBDBM50512573(CHEMBL4476654)
Affinity DataIC50:  25nMAssay Description:Inhibition of PHGDH (unknown origin) using 11 nM of PHGDH and 3-PG as substrate incubated for 20 mins in presence of NAD+, PSAT1, PSPH by diaphorase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed