BDBM50513226 CHEMBL4475303

SMILES CCN1CCc2c(C1)c1ccccc1n2CCC(=O)N1c2ccccc2Sc2ccccc12

InChI Key InChIKey=KKVLXBBVHBRIJD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50513226   

TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50513226(CHEMBL4475303)
Affinity DataIC50: 520nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Jining Medical University

Curated by ChEMBL
LigandPNGBDBM50513226(CHEMBL4475303)
Affinity DataIC50: 520nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50513226(CHEMBL4475303)
Affinity DataIC50: 1.34E+4nMAssay Description:Displacement of [3H]-ifenprodil from NMDA receptor (unknown origin) by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50513226(CHEMBL4475303)
Affinity DataIC50: 1.34E+4nMAssay Description:Displacement of [3H]ifenprodyl from NMDA receptor NR2B subunit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50513226(CHEMBL4475303)
Affinity DataIC50: 1.46E+4nMAssay Description:Displacement of [3H]-MK-801 from NMDA receptor (unknown origin) by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Northwest A&F University

Curated by ChEMBL
LigandPNGBDBM50513226(CHEMBL4475303)
Affinity DataIC50: 1.46E+4nMAssay Description:Displacement of [3H]MK801 from NMDA receptor NR2B subunit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50513226(CHEMBL4475303)
Affinity DataIC50: 1.46E+4nMAssay Description:Displacement of [3H]MK-801 from NMDA receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed