BDBM50513551 CHEMBL4447310

SMILES CCCCc1nc(\C=N\Nc2nc(N)c3ncn([C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)c3n2)c(Cl)[nH]1

InChI Key InChIKey=RURQHXBBEOQUIE-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50513551   

TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513551(CHEMBL4447310)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513551(CHEMBL4447310)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]DPCPX from human cloned adenosine receptor A1 expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
National Engineering Research Center For The Emergency Drug

Curated by ChEMBL
LigandPNGBDBM50513551(CHEMBL4447310)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]CGS21680 from human cloned adenosine receptor A2A expressed in HEK-293 cell membrane incubated for 60 mins by microbeta counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed