BDBM50513919 CHEMBL4457162

SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3cccnc23)cc1

InChI Key InChIKey=PBCHBJALYWYEAP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50513919   

TargetHistone deacetylase 6(Human)
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50513919(CHEMBL4457162)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50513919(CHEMBL4457162)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50513919(CHEMBL4457162)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50513919(CHEMBL4457162)
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of recombinant C-terminal His/FLAG-tagged human HDAC1 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Ludwig-Maximilians University Munich

Curated by ChEMBL
LigandPNGBDBM50513919(CHEMBL4457162)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human HDAC8 expressed in baculovirus expression system using fluorogenic Arg-His-Lys(Ac)-Lys(Ac) as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed