BDBM50514283 CHEMBL4524872

SMILES Oc1ccc2c(Oc3ccc(OCCN4CC(CF)C4)cc3)c(sc2c1)C(=O)c1ccc(F)cc1

InChI Key InChIKey=SLDDUMSXIWGHHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514283   

TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514283(CHEMBL4524872)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514283(CHEMBL4524872)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed