BDBM50514286 CHEMBL4448178

SMILES Cc1ccccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(OC2CN(CCCF)C2)cc1

InChI Key InChIKey=IDVXSRPEUSTBBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514286   

TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514286(CHEMBL4448178)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at ERalpha in human MCF7:WS8 cells incubated for 18 hrs by dual luciferase reporter gene assay relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50514286(CHEMBL4448178)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of ERalpha in human MCF7:WS8 cells assessed as increase in degradation of ERalpha incubated for 24 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed