BDBM50514623 CHEMBL4457477

SMILES CCOC(=O)N1CCC2(CC1)C[C@H](NC(=O)c1cccc3cc[nH]c13)c1cc(Br)ccc1O2

InChI Key InChIKey=DXSQRTKUOQZVDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514623   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514623(CHEMBL4457477)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of IDO1 in IFN-gamma/LPS stimulated human PBMC assessed as reduction in kynurenine production after 48 hrs by RapidFire MS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed