BDBM50514765 CHEMBL4549709

SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc-2c(c1)-c1ccc(cc-21)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@H](N(C)C)c1ccccc1

InChI Key InChIKey=QXVRMMRUZPFBBJ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50514765   

TargetNonstructural protein 5A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514765(CHEMBL4549709)
Affinity DataEC50:  0.0140nMAssay Description:Inhibition of NS5A in HCV genotype 1b infected in HuH-Lcu-Neo cells assessed as reduction in viral replication incubated for 48 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514765(CHEMBL4549709)
Affinity DataEC50:  0.0530nMAssay Description:Inhibition of NS5A in HCV genotype 1a infected in HuH-Lcu-Neo cells assessed as reduction in viral replication incubated for 48 hrs by luciferase rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50514765(CHEMBL4549709)
Affinity DataEC50:  1.47nMAssay Description:Inhibition of NS5A in HCV genotype 2a con infected in HuH-Lcu-Neo cells assessed as reduction in viral replication incubated for 48 hrs by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed