BDBM50514806 CHEMBL4452260

SMILES CSc1nnc(CCCO)n1-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=GJDAEBFYCKWWQJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514806   

TargetToll-like receptor 8(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514806(CHEMBL4452260)
Affinity DataIC50: 190nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed