BDBM50514918 CHEMBL4457759

SMILES CCc1c2Cn3c(cc4c(COC(=O)[C@@]4(CC)OC(=O)CCNC(=O)CNc4cc(ccc4C(N)=O)-n4nc(c5c4CC(C)(C)CC5=O)C(F)(F)F)c3=O)-c2nc2ccc(O)cc12

InChI Key InChIKey=JVIITDLFNRFHSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50514918   

TargetHeat shock protein HSP 90-alpha(Human)
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50514918(CHEMBL4457759)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant human full length HSP90 alpha expressed in Escherichia coli cells after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed