BDBM50515240 CHEMBL4437740

SMILES C[C@H]1CO[C@H](CN1C[C@@H]1C[C@H]1CCNC(=O)c1cc2ccccc2[nH]1)c1ccc(N)nc1

InChI Key InChIKey=JQBHQHNVJCDNEL-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50515240   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  282nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from recombinant human D3 receptor expressed in HEK293 cell membranes measured after 90 mins by microbeta scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  282nMAssay Description:Displacement of [3H]-(R)-(+)7-OH-DPAT from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  831nMAssay Description:Displacement of [3H]-(R)-(+)7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  831nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from recombinant human D2L receptor expressed in HEK293 cell membranes measured after 90 mins by microbeta sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]-methylscopolamine from human dopamine D3 receptor expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  2.93E+3nMAssay Description:Displacement of [3H]-(R)-(+)-7-OH-DPAT from recombinant human D4.4 receptor expressed in HEK293 cell membranes measured after 90 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  6.27E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  7.06E+4nMAssay Description:Displacement of [3H]-methylscopolamine from human dopamine D2 receptor expressed in HEK293 cell membranes incubated for 90 mins by microbeta scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse?Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50515240(CHEMBL4437740)
Affinity DataKi:  7.06E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed