BDBM50515320 CHEMBL4441630
SMILES Clc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1
InChI Key InChIKey=DJSUCHMXQOIATH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50515320
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataKi: 0.0420nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataKi: 59nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.29E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair