BDBM50515320 CHEMBL4441630

SMILES Clc1cccc(NC(=O)c2cncc(c2)N2CC3CC(C2)N3)c1

InChI Key InChIKey=DJSUCHMXQOIATH-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50515320   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515320(CHEMBL4441630)
Affinity DataKi:  0.0420nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cerebral cortex membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515320(CHEMBL4441630)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]epibatidine from human alpha3beta4 nAChR transfected in HEK243 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515320(CHEMBL4441630)
Affinity DataKi:  2.29E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50515320(CHEMBL4441630)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in GH4C1 cells assessed as increase in inward channel current measured after 3 to 4 days at -70...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed