BDBM50515471 CHEMBL4531167

SMILES Oc1ccc(CCOCCCCCNc2c3CCCCc3nc3ccccc23)cc1

InChI Key InChIKey=AZMKNSQZSVBTKB-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50515471   

TargetCholinesterase(Horse)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50515471(CHEMBL4531167)
Affinity DataKi:  4.5nMAssay Description:Inhibition of equine serum BuChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using butyrylthiocholine iodide as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50515471(CHEMBL4531167)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human serum BuChe by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50515471(CHEMBL4531167)
Affinity DataKi:  100nMAssay Description:Inhibition of electric eel AChE assessed as dissociation constant for enzyme-substrate-inhibitor complex using acetylthiocholine iodide as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50515471(CHEMBL4531167)
Affinity DataKi:  140nMAssay Description:Inhibition of electric eel AChE assessed as dissociation constant for enzyme-inhibitor complex using acetylthiocholine iodide as substrate measured f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50515471(CHEMBL4531167)
Affinity DataIC50: 142nMAssay Description:Inhibition of human recombinant AChE expressed in HEK293 cells using acetylcholine iodide as substrate preincubated with enzyme for 20 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed