BDBM50516202 CHEMBL4454887

SMILES COc1c(Cl)cc(cc1Cl)-c1ccc(s1)C(=O)c1c(Cl)ccc(O)c1F

InChI Key InChIKey=LJMPWLXEXUGLHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50516202   

Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50516202(CHEMBL4454887)
Affinity DataIC50:  15nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandPNGBDBM50516202(CHEMBL4454887)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human placental cytosolic fraction 17beta-HSD1 using [3H]-E1 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed