BDBM50516405 CHEMBL4552555
SMILES CC(C)Oc1cc(ccc1F)[C@@](Cc1ccccc1)(NCC(O)C(O)(C(F)(F)F)C(F)(F)F)c1cc(F)cc(OC(F)(F)C(F)F)c1
InChI Key InChIKey=PEZNRHPWKBCSLM-JUERFOTFSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50516405
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of CETP in human whole plasma assessed as reduction in [3H]-CE/HDL transfer incubated for 2.5 hrs by topcount scintillation counting assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bristol-Myers Squibb
Curated by ChEMBL
Bristol-Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair