BDBM50517805 CHEMBL4454648

SMILES CC(C)CC(NC(=O)c1cccc(c1)-c1ccc(cc1)S(C)(=O)=O)C(=O)N(C)N(C)C#N

InChI Key InChIKey=MKAMNFYJFXAVNX-UHFFFAOYSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50517805   

TargetCathepsin K(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517805(CHEMBL4454648)
Affinity DataKi:  7.20nMAssay Description:Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517805(CHEMBL4454648)
Affinity DataKi:  406nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517805(CHEMBL4454648)
Affinity DataKi:  735nMAssay Description:Inhibition of recombinant human cathepsin S expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517805(CHEMBL4454648)
Affinity DataKi:  3.35E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517805(CHEMBL4454648)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant His-tagged human cathepsin K expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517805(CHEMBL4454648)
Affinity DataIC50:  3.37E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517805(CHEMBL4454648)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of recombinant human cathepsin S expressed in Escherichia coliMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Jilin University

Curated by ChEMBL
LigandPNGBDBM50517805(CHEMBL4454648)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed