BDBM50518056 CHEMBL1160787

SMILES c1ccc(cc1)[C@H]2CNCCc3c2cc(c(c3Cl)O)O

InChI Key InChIKey=GHWJEDJMOVUXEC-UHFFFAOYSA-N

Data  2 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518056   

TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518056(CHEMBL1160787)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as reversal of Ro 20-1724 mediated decrease in cAMP accumulation aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50518056(CHEMBL1160787)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as assessed as increase in beta-arrestin-2 recruitment after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)