BDBM50518228 CHEMBL4445920

SMILES NS(=O)(=O)c1cccc(Nc2nc(NCc3ccccc3)c3ccccc3n2)c1

InChI Key InChIKey=AWVQNXPWVWEELS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518228   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rat)
Kasetsart University

Curated by ChEMBL
LigandPNGBDBM50518228(CHEMBL4445920)
Affinity DataIC50: 72nMAssay Description:Inhibition of rat lung PDE5 using [3H]cGMP as substrate measured after 10 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50518228(CHEMBL4445920)
Affinity DataIC50: 100nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed