BDBM50518648 CHEMBL4438364

SMILES CCCCCCCCCCCCNC(=O)CCCCC[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CCC(=O)NCC(=O)NCCCC[C@H](NC1=O)C(N)=O

InChI Key InChIKey=CMBYZABOYISXFV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50518648   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50518648(CHEMBL4438364)
Affinity DataIC50: 550nMAssay Description:Inhibition of deacetylation activity of recombinant human N-terminal His6-tagged SIRT2 (2 to 389 residues) expressed in Escherichia coli using H2N-HK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50518648(CHEMBL4438364)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of deacetylation activity of recombinant human N-terminal His6-tagged SIRT3 (101 to 399 residues) expressed in Escherichia coli using H2N-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50518648(CHEMBL4438364)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of recombinant human SIRT1 deacetylase activity using H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH as substrate measured after 10 mins by HPLC ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50518648(CHEMBL4438364)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tRNA-activated deacetylation activity of recombinant human full length N-terminal His6-tagged SIRT7 expressed in Escherichia coli using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-6(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50518648(CHEMBL4438364)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of demyristoylation activity of recombinant human full length N-terminal His6-tagged SIRT6 expressed in Escherichia coli using H2N-EALPK-[...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Human)
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50518648(CHEMBL4438364)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of desuccinylation activity of recombinant human full length N-terminal GST-tagged SIRT5 expressed in Escherichia coli using CH3CONH-AR-[N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed