BDBM50519452 CHEMBL4520400
SMILES CC(C)(C)c1ccc(CN(C(=O)CN(Cc2c(F)c(F)c(F)c(F)c2F)S(=O)(=O)c2ccc(F)cc2)c2ccc(cc2)C(=O)NO)cc1
InChI Key InChIKey=LTRKEOBJRDKIHB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50519452
Affinity DataKi: 3.60E+3nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells assessed as inhibitory constant using FAM-RHKK-Ac as su...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC8 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 3 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 5 hrs by e...More data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
University of Toronto Mississauga
Curated by ChEMBL
University of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 636nMAssay Description:Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 17 hrs ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human HDAC8 expressed in SF9 baculoviral system using FAM-labeled acetylated peptide as substrate by EMSAMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human HDAC6 expressed in SF9 baculoviral system using FAM-labeled acetylated peptide as substrate by EMSAMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
University of Toronto Mississauga
Curated by ChEMBL
University of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 636nMAssay Description:Inhibition of recombinant human HDAC11 expressed in SF9 baculoviral system using FAM-labeled acetylated peptide as substrate by EMSAMore data for this Ligand-Target Pair
Affinity DataIC50: 654nMAssay Description:Inhibition of recombinant human HDAC3 expressed in SF9 baculoviral system using FAM-labeled acetylated peptide as substrate by EMSAMore data for this Ligand-Target Pair
Affinity DataIC50: 654nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 3 hrs by e...More data for this Ligand-Target Pair