BDBM50519458 CHEMBL4563224
SMILES ONC(=O)c1ccc(cc1)N(Cc1ccccc1)C(=O)CN(Cc1c(F)c(F)c(F)c(F)c1F)S(=O)(=O)c1ccc(F)cc1
InChI Key InChIKey=RRXUMIHVJXZUFJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50519458
Affinity DataKi: 1.86E+3nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells assessed as inhibitory constant using FAM-RHKK-Ac as su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 5 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 132nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in baculovirus infected Sf9 cells using FAM-RHKK-Ac as substrate incubated for 3 hrs by e...More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of recombinant full length human HDAC8 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 3 hrs by...More data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
University of Toronto Mississauga
Curated by ChEMBL
University of Toronto Mississauga
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 17 hrs ...More data for this Ligand-Target Pair