BDBM50520827 CHEMBL4536146

SMILES CNCCN(C)c1cc(OC)c(Nc2nccc(n2)-c2cn(C)c3cccnc23)cc1NC(=O)C=C

InChI Key InChIKey=JCAVYERIDLVMRV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50520827   

TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520827(CHEMBL4536146)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M/L858R double mutant (696-end residues) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520827(CHEMBL4536146)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in baculovirus expression system by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wuxi Shuangliang Biotechnology

Curated by ChEMBL
LigandPNGBDBM50520827(CHEMBL4536146)
Affinity DataIC50: 2.77E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (696-end residues) expressed in baculovirus expression system using Srctide as substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed