BDBM50521514 CHEMBL4532845

SMILES CCOC1Cc2ccccc2[C@@]2(CC[C@@H](CC2)NCC2CCCCC2)O1

InChI Key InChIKey=LKSVIRCJQQMHGO-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50521514   

TargetSigma intracellular receptor 2(Human)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50521514(CHEMBL4532845)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in human RT4 cell membranes incubated for 120 mins in the presence of sigma1 receptor l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50521514(CHEMBL4532845)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]U69,593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50521514(CHEMBL4532845)
Affinity DataKi:  161nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins in the presence of sigma1 receptor ligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50521514(CHEMBL4532845)
Affinity DataKi:  183nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50521514(CHEMBL4532845)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50521514(CHEMBL4532845)
Affinity DataKi:  185nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed