BDBM50521591 CHEMBL4562244

SMILES CC(=O)N1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO

InChI Key InChIKey=PLZLTKONMCWPLT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50521591   

TargetHistone deacetylase 6(Human)
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50521591(CHEMBL4562244)
Affinity DataIC50: 79nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC6 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50521591(CHEMBL4562244)
Affinity DataIC50: 501nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
European Molecular Biology Laboratory

Curated by ChEMBL
LigandPNGBDBM50521591(CHEMBL4562244)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed