BDBM50522515 CHEMBL4582933

SMILES COc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)CC1CCSS1

InChI Key InChIKey=ZMJYLUUUDNJQQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50522515   

TargetEpidermal growth factor receptor(Human)
Sabila Biosciences

Curated by ChEMBL
LigandPNGBDBM50522515(CHEMBL4582933)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of probe binding to EGFR L858R mutant (unknown origin) using rabbit reticulate lysate system after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sabila Biosciences

Curated by ChEMBL
LigandPNGBDBM50522515(CHEMBL4582933)
Affinity DataIC50: 25nMAssay Description:Inhibition of probe binding to wild type EGFR (unknown origin) using rabbit reticulate lysate system after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed