BDBM50522587 CHEMBL4453551

SMILES Clc1ccc(s1)S(=O)(=O)Nc1ccc(cc1)-c1nc2cc(NS(=O)(=O)c3cccc4ccccc34)ccc2o1

InChI Key InChIKey=LDXXAJNFRZDMIC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50522587   

TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50522587(CHEMBL4453551)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis His-tagged PtpB expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 30 mins by spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50522587(CHEMBL4453551)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human PTPN5 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50522587(CHEMBL4453551)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human PTPN1 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50522587(CHEMBL4453551)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human PTPN2 expressed in Escherichia coli Rosetta 2 (DE3) using pNPP as substrate after 45 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed